Drug Index


Mechanism :

It is a macrolide bacteriostatic antibiotic with activity against most gram-positive and gram-negative organisms. It is used in the treatment of certain respiratory tract infections (pneumonia, bronchitis, sinusitis, pharyngitis) and urinary tract infections.

Indication :

  • Treatment of respiratory, urinary and soft tissue infections.

Dosing :

8-10 mg/kg/day PO in 2 divided doses.

Adverse Effect :

Nausea, vomiting, diarrhea, elevated liver enzymes and rarely, rashes.

Interaction :

Cyclosporine: The macrolide, roxithromycin, may increase the effect of cyclosporine.

Hepatic Dose :

Severe hepatic impairment: Give half the dose
01/18/2024 19:43:13 Roxithromycin
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