Drug Index

Sodium Picosulfate

 
print
Synonym :

Sodium Picosulphate

Mechanism :

Sodium Picosulfate increases peristalsis (stimulant laxative); magnesium citrate, formed by magnesium oxide and citric acid, increases peristalsis (osmotic laxative).


Indication :

• Constipation


Contraindications :

Hypersensitivity to drug/class/component, CrCl <30, uncorrected Electrolyte abnormalities, Intestinal perforation, GI obstruction, Toxic colitis, Toxic megacolon or ileus, Gastric retention.

Caution if severe ulcerative colitis, arrhythmia risk, renal impairment, concurrent nephrotoxic agent use, seizure history or risk, aspiration risk, impaired gag reflex, prior or concurrent antibiotic use.


Dosing :

Give orally.

>10 years: 5-10 mg per day.

4-10 years: 2.5-5 mg per day.

<4 years: 0.25 mg/kg/day.


Adverse Effect :

Serious Reactions: Electrolyte imbalance, renal failure, seizures, arrhythmia, ischemic colitis, colonic mucosal aphthous ulcer, nausea, headache, vomiting, abdominal cramps/distension, hyponatremia, hypokalemia, hypermagnesemia, hypocalcemia, hypochloremia, hypersensitivity reaction.


Interaction :

Avoid/Use Alternative:
Calcitriol, Doxercalciferol, Ursodiol.


07/14/2019 06:49:25 Sodium Picosulfate
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0