Drug Index

Sorbitol

 
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Mechanism :

It is a sugar that occurs naturally in fruits and vegetables and is used as a sweetening agent especially in the case of diabetic foods. It is also used in the treatment of constipation.


Indication :

• Constipation


Contraindications :

Acute abdominal pain, nausea, vomiting, or other symptoms of appendicitis or undiagnosed abdominal pain.


Dosing :

<2 years: Safety and efficacy not established.

2-11 years:

Oral: 2 mL/kg (as 70% solution) once.

Rectal enema: 30-60 mL as 25-30% solution.

>12 years:

Oral: 30-150 mL (70% solution) once.

Rectal enema: 120 mL of 25-30% solution once.


Adverse Effect :

Diarrhea, dehydration, electrolyte losses, hyperglycemia, lactic acidosis, vomiting.


Interaction :

Sodium Polystyrene Sultanate: Combination is implicated in colonic necrosis.


07/14/2019 19:43:14 Sorbitol
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