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Overdiagnosis of Tuberculosis and Role of Tuberculin Test
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Received 13 March 2021
Accepted 3 August 2021

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https://doi.org/10.7199/ped.oncall.2022.35

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Parikh S, Shah I, Paikrao P. Overdiagnosis of Tuberculosis and Role of Tuberculin Test. Pediatr Oncall J. 2021 Aug 03. doi: 10.7199/ped.oncall.2022.35
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ORIGINAL ARTICLE
Overdiagnosis of Tuberculosis and Role of Tuberculin Test
Shefali Parikh, Ira Shah, Pradnya Paikrao.
Pediatric TB Clinic, Department of Pediatric Infectious Diseases, B J Wadia Hospital for Children, Mumbai, India.
Abstract
This is a retrospective analysis of children who were referred to our tuberculosis (TB) clinic from March 2010 to Feb 2011 but were not started on ATT and none of them subsequently developed TB. Interpretation of tuberculin test as a means of diagnosis was analysed.
Results: Thirty-four (11.2%) children were overly diagnosed as TB. Seventeen out of 28 referred children were tuberculin positive and 8 were tuberculin negative. Also, 12 of tuberculin positive children had a reading of ≥15mm, yet none of them developed active disease. Although 2 TU is the recommended standard dose for tuberculin testing in India, in our study no child had received 2 TU, 23.5% of tuberculin positive patients had received a 5 TU dose and 35.3% a 10 TU dose.
Conclusion: Most children with over-diagnosis of TB receive TT with more than 2TU units. The size of tuberculin reaction needs to be interpreted carefully.

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