ISSN - 0973-0958

Pediatric Oncall Journal View Article

Breathlessness in a Child Exposed to COVID-19
Meghana Phadke, Vishwajeet Sonu, N R Harish.
Department of Pediatrics, Metro Heart and Super Specialty Hospital, Faridabad, Haryana, India.
A 4-year-old boy suffering from celiac disease on gluten free diet and in close contact with a COVID-19 patient for 2 weeks presented with fever 101 degree F, diarrhea and breathlessness with hypoxia. COVID-19 RT PCR and inflammatory markers were negative. There was pneumothorax on right side with lacy bullous pattern on chest x-ray. CT chest showed bilateral cystic lung disease. Lung biopsy showed moderately dense diffuse nodular infiltrates of oval to medium sized Langerhans cells. It also showed CD1a and S100 positivity on immunohistochemistry confirming Langerhans Cell Histiocytosis (LCH). There was no bone, skin, liver, or lymph node affected suggestive of isolated pulmonary LCH.

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