ISSN - 0973-0958

Pediatric Oncall Journal View Article

Urine toxicology screen: What challenges?
Bárbara Barroso de Matos, Débora Aroeira Mendes, Nélia Santos Gaspar, Sara Ferreira.
Department of Pediatrics, Médio Tejo Hospital Center, Torres Novas, Portugal.
The urine toxicology screen is a test widely used in clinical practice, but it may be subject to false positive or negative results. With regard to opioid screen, one of the causes of false positives is the ingestion of poppy seeds. The authors describe the case of an adolescent who performed a urine toxicology screen in the context of a first seizure episode, which revealed the presence of morphine. After a detailed anamnesis, the teenager reported having consumed crackers with poppy seeds the night before. The opium poppy is widely used in the food industry, mainly through its seeds. This clinical case alerts us to the possibility of false positives in toxic screening tests after ingesting poppy seeds. This situation can be a problem as it can have medical-legal implications. For this reason, the cut-off value of 300 ng/ml used by most laboratories in many countries has been frequently discussed.

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