ISSN - 0973-0958

Pediatric Oncall Journal View Article

Van Wyk-Grumbach syndrome: A Rare Result of Prolonged Hypothyroidism
Mahantesh Matti, Suhas Joshi.
Department of Pediatrics, SDM College of Medical Sciences and Hospital, Sattur, Dharwar, Karnataka, India.
Van Wyk-Grumbach syndrome is a rare disease characterized by prolonged hypothyroidism, precocious puberty with multicystic enlarged ovaries and features of polycystic ovarian disease (PCOD). Thyroxin replacement resolves symptoms of hypothyroidism and also symptoms of PCOD. Diagnosing this syndrome is important as unnecessary investigations for cystic enlarged ovaries can be avoided. We report a 12 years old girl who presented with obesity and features of insulin resistance. On evaluation she was found to be hypothyroid with high levels of thyroid stimulating hormone (TSH) and ultrasound of pelvis revealed ovarian cysts.

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