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Celiac disease associated with Graves Disease

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Volume 12, Issue 3

July-September 2015
Pages: 78-79

DOI:
https://doi.org/10.7199/ped.oncall.2015.39

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Jellouli M, Thraya S, Zarrouk C, Abidi K, Khiari K, Gargah T. Celiac disease associated with Graves Disease. Pediatr Oncall J. 2015;12: 78-79. doi: 10.7199/ped.oncall.2015.39

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CASE REPORTS

Celiac disease associated with Graves Disease

Manel Jellouli¹, Souhir Thraya¹, Chokri Zarrouk¹, Kamel Abidi¹, Karima Khiari², Tahar Gargah¹.

¹Department of Pediatric Nephrology, Charles Nicolle Hospital, Tunis, Tunisia,
²Department of Medicine Interne A Department, Charles Nicolle Hospital, Tunis, Tunisia.

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Abstract
Celiac disease is an autoimmune enteropathy induced by gluten intake in genetically susceptible individuals. Celiac disease is known to be associated with autoimmune diseases. However the association celiac disease, Graves' disease and selective IgA deficiency are rarely found in children. A 4 years-old girl with celiac disease and selective IgA deficiency presented with diarrhea and growth acceleration. Thyroid tests showed hyperthyroidism with positive thyroid receptor antibodies, confirming the presence of Graves’ disease. HLA typing showed the haplotype A23 851 A28 03 DRB1 * B3. Screening for other autoimmune disorders was negative. Treatment with carbimazole was started and the patient soon became euthyroïd. Carbimazole was stopped after 18 months of follow-up.

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