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Neuroblastoma with eye involvement
Rakesh Kumar, Binay Ranjan, Manjul Vijay.
Department of Pediatrics, Katihar medical college, Katihar, Bihar, India.
ADDRESS FOR CORRESPONDENCE
Rakesh Kumar, Department of Pediatrics, Katihar medical college, Katihar, Bihar, India.
Email: drjaiswalrakesh@yahoo.co.in
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What is the eye lesion called?
Raccoon eyes. Neuroblastoma {NB} is the fourth most common malignancy of childhood preceded by leukaemia, central nervous system tumour and lymphomas. More than 50 percent of patients with NB present with signs and symptoms of metastatic disease. Patients with metastasis to retrobulbar region present with proptosis {1,2}. The raccoon eyes appearance in NB is probably related to obstruction of the palpebral vessels {branches of the ophthalmic and facial vessels} by tumour tissue in and around the orbits {1,2}. The present case was unique because apart from anaemia, the only major finding was raccoon eyes in the patient. This was probably because of early metastasis to periorbital region, than in other organs. Only one similar case has been reported recently from outside India {3}. The correct diagnosis of the condition is sometimes delayed because of work up for trauma or child abuse {1,4}. Apart from NB, other malignancies associated with raccoon eyes include multiple myeloma, lymphoma and Kaposi’s sarcoma {4}. Traumatic conditions like thoracic crush injuries, maxillofacial trauma, acute subdural bleeding or just plucking of eyebrows are also known to cause raccoon eyes {5}. Other conditions associated with raccoon eyes are migraine, chronic cocaine abuse and endocrine problem like myxoedema {5}. The present case highlights the importance of raccoon eyes as one of the presenting sign of neuroblastoma in children.
E-published: May 2013 Vol 10 Issue 5 Art # 25 |
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Funding: None
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Conflict of Interest: None
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DOI: https://doi.org/10.7199/ped.oncall.2013.25 |
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Cite this article as:
Kumar R, Ranjan B, Vijay M. Neuroblastoma with eye involvement (Raccoon eyes). Pediatr Oncall J. 2013;10: 64. doi: 10.7199/ped.oncall.2013.25
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