Benzodiazapines
 
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They are used as anti – anxiety and muscle relaxing agents The commonly used preparations are: Diazepam, flurazepam, chlordiazepoxide, nitrazepam, oxazepam, alprazolam, lorazepam
Route :
Ingestion
Fatal Dose :
60 to 100ml
Fatal Period :
few hrs
Mechanism of action :
They enhance the inhibitory action of neurotransmitter GABA an the brain
Clinical Picture :
• Vertigo, slurred speech, nystagmus, diplopia, dysarthria, ataxia • Sedation, somnolence, coma
Treatment :
• Gastric lavage with sodium bicarbonate • Activated charcoal • high colonic irrigation • Calcium gluconate and dextrose i.v. • Symptomatic
08/06/2019 12:24:35 Benzodiazapines
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