Chlorate
 
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Sodium salt {resembles table salt} is more toxic than potassium salt
Route :
Ingestion
Fatal Dose :
20 to 30gm
Mechanism of action :
•It is a powerful osxidising agent and attacks all body cells. It oxidizes hemoglobin to methemoglobin
Clinical Picture :
•Nausea, vomiting, colicky pain and diarrhea •Blood, protein and hemoglobin in urine, oliguria, anuria and renal failure •Hemolysis, jaundice and hepatic failure •If methhemoglobin levels reach 40 percent or more : agitation, weakness, convulsions and muscular twichings and death due to renal failure
Treatment :
•Stomach wash with warm water or sodium bicarbonate •Methylene blue 25 ml 1 percent solution i.v.and ascorbic acid 1gm •peritoneal dialysis or hemodialysis •Symptomatic
07/14/2019 01:43:23 Chlorate
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