Aluminium Phosphide (cephlos) - Poisoning Center

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Aluminium phosphide (cephlos)

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It is white or grey tablets with garlicky odor.
Route :
Ingestion or inhalation
Fatal Dose :
one tablet (3gm)
Fatal Period :
24 hours
Mechanism of action :
It is due to phosphine gas {PH3} gas released on contact with gastric Hcl. Phosphine inhibits respiratory chain enzymes and has cyto toxic action.
Clinical Picture :
•dizziness •vomiting •diarrhea •respiratory distress •cyanosis •cardiac arrhythmia •circulatory failure •convulsions
Treatment :
•Gastric lavage with sodium bicarbonate •Activated charcoal •Antacids reduce absorption of phosphine •Magnesium reduces organ toxicity, hypomagnesia amd arrhthmias •Symptomatic

Aluminum phosphide Carbamates

Chlorate Dinitro compounds

Organophosphorous compounds Paraquat

Pyrethrins and pyrethroids

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