Aluminium phosphide (Cephlos)
It is white or grey tablets with garlicky odor.
Route :
Ingestion or inhalation
Fatal Dose :
one tablet (3gm)
Fatal Period :
24 hours
Mechanism of action :
It is due to phosphine gas {PH3} gas released on contact with gastric Hcl. Phosphine inhibits respiratory chain enzymes and has cyto toxic action.
Clinical Picture :
•dizziness
•vomiting
•diarrhea
•respiratory distress
•cyanosis
•cardiac arrhythmia
•circulatory failure
•convulsions
Treatment :
•Gastric lavage with sodium bicarbonate
•Activated charcoal
•Antacids reduce absorption of phosphine
•Magnesium reduces organ toxicity, hypomagnesia amd arrhthmias
•Symptomatic
Pediatric Oncall
12/19/2020 09:23:36
12/19/2020 09:23:36
Aluminium phosphide (Cephlos)