Paraldehyde
 
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This is a clear colorless liquid having an ethereal odor and an acrid nauseous taste. It is used a hypnotic and as basal anesthetic.
Route :
Ingestion
Fatal Dose :
60 to 100ml
Fatal Period :
few hrs
Mechanism of action :
It is absorbed rapidly from the stomach and small intestine and also from the rectum. Is is metabolized in liver to trichloroethanol which is hypnotic.
Clinical Picture :
• nausea, vomiting, eructations, headache and giddiness • breath smells of paraldehyde • drowsiness, slow pulse, shallow breathing, dilated pupils, cyanosis • Subnormal temperature, coma
Treatment :
• Gastric lavage with sodium bicarbonate • Activated charcoal • high colonic irrigation • Calcium gluconate and dextrose i.v. • Symptomatic
07/14/2019 01:40:34 Paraldehyde
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