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Question of the Week
Question :
Posted On :
26 Jun 2007
WHEN SOULD WE LABEL A CASE OF MALARIA AS "RESISTANT MALARIA"?
5
Expert Answer :
No expert answer available.
Answer Discussion :
P
pramod m.kulkarni
0
clinically-persistent fever even after appropriate,complete,assimilated parasiticidal dose of an antimalarial agent.
scientifically-WHO defn and resistance category
persistent parasitemia even after adequate assimilated dose of an antimalarial agent.
17 years ago
D
Dr Sheila Emmanuel
0
When thereis no response to routinely used drugs
17 years ago
S
safy nawar
0
resistant malaria considerd with failure of eradication of parasite through 7-28 days
17 years ago
D
Dr.D.Nagesh
0
when the disease is not responded inspite of using chloroquine, quinine.
17 years ago
P
pediatriconcall
0
WHO has developed a simple scheme for estimating the degree of resistance that involves studying the parasitemia over 28 days. Smears on day 2, 7 and 28 are done to grade the resistance as R1 to R3. In a case of normal response parasite count to fall to 25 Percent of pre-treatment value by 48 hours and smear should be negative by 7 days.
RI, Delayed Recrudescence: The asexual parasitemia reduces to Less than 25 Percent of pre-treatment level in 48 hours, but reappears between 2-4 weeks.
RI, Early Recrudescence: The asexual parasitemia reduces to Less than 25 Percent of pre-treatment level in 48 hours, but reappears earlier.
RII Resistance: Marked reduction in asexual parasitemia {decrease More than 25 Percent but Less than 75 Percent} in 48 hours, without complete clearance in 7 days.
RIII Resistance: Minimal reduction in asexual parasitemia, {decrease Less than 25 Percent} or an increase in parasitemia after 48 hours.
18 years ago
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