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Q. A 6-month female infant born to G2 with a history of previous spontaneous abortion to an nc married couple presented with a history of jaundice, clay-colored stools(intermittently) since 2nd week of life (now 5mths 15 days), no e, o neurological impairment, developmentally normal, presently playful, serially investigated to find bilirubin always more than 6 m percent (direct More than 5 mg percent), recently admitted with tsb=16 mg percent (pre dominantly conjugated) for evaluation, prothrombin time on several occasions abnormal (inr More than 2), on regular treatment with inj. vit k, sr. proteins now within normal range, sgot, sgpt raised, alk. phosphatase raised up to 806 iu, urine for reducing sugars being negative. Advice on further steps and management.

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