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WHO says e-cigarettes, 'smoke-free' products do not help reduce cancer. Should e-cigarettes be banned?
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Toronto childhood cancer staging criteria for neuroblastoma
Toronto Childhood Cancer Staging criteria for Neuroblastoma
TIER 1
Localized
Localized tumour not involving vital structures and confined to one body compartment
Locoregional
Locoregional tumour with spread
Metastatic
Distant metastatic disease (except stage MS)
MS
Metastatic disease confined to skin, liver, and/or bone marrow in a patient less than 18 months (547 days).
TIER 2
Stage L1
Localized tumour that does not involve any vital structures as defined by the list of IDRFs (i.e. there are no IDRFs) and the tumour must be confined within one body compartment, neck, chest, abdomen, or pelvis.
or
An intraspinal tumour extension that does not fulfil the criteria for an IDRF is consistent with stage L1.
Stage L2
Locoregional tumour with one or more IDRFs.
or
The tumour may be ipsilaterally contiguous within body compartments (ie, a left sided abdominal tumour with left-sided lung, bone or pleura involvement should be considered stage L2).
or
However, a clearly left sided abdominal tumour with right-sided lung, bone or pleura (or vice versa) involvement is defined as metastatic disease.
Stage M
Distant metastatic disease (ie, not contiguous with the primary tumour) except as defined for stage MS.
or
Nonregional (distant) lymph node involvement is metastatic disease. However, an upper abdominal tumour with enlarged lower mediastinal nodes or a pelvic tumour with inguinal lymph node involvement is considered locoregional disease.
or
Ascites and/or a pleural effusion, even with malignant cells, do not constitute metastatic disease unless they are remote from the body compartment of the primary tumour.
Stage MS
Metastatic disease confined to skin, liver, and/or bone marrow, in a patient less than 18 months (547 days).
or
MIBG scintigraphy must be negative in bone and bone marrow.
Result :
Diagnostic criteria
not met
.
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