LYMLPHOPENIA IN TB

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LYMLPHOPENIA IN TB

Author: Pediatric Oncall

Question
A 7 years old boy had fever with limping 4 months back and left hip arthritis was detected for which arthrotomy was done and pus smear showed acid fast bacilli {AFB}. He was started on 4 drug antituberculous therapy {ATT}. His culture also grew mycobacterium tuberculosis {MTB} sensitive to all first line drugs. His hemogram 4 months ago showed lymphopenia {882 cells, cumm} which again after 4 months of therapy was 1364 cells, cumm. HIV ELISA was negative.

What is the cause of lymphopenia_?

Answer Discussion :

A

Abdul Rashid

0

Refractory lymphopenia due to severe infection

13 years ago

M

MUSTAFA SAAD

0

from tuberculous infection

13 years ago

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Answer 1

Tuberculosis is one of the numerous conditions that may temporarily diminish lymphocyte subpopulations, producing the lymphocytopenia observed in some patients. Lymphopenia in patients with Tb is unrelated to the extent of lesions and prognosis. However it could be associated to a higher frequency of paradoxical reactions

LYMLPHOPENIA IN TB

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