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TB culture
Author:
Pediatric Oncall
Question
A 6½ years old HIV infected girl on antiretroviral therapy {ART} for 1½ years consisting of
Stavudine
{d4T},
Lamivudine
{3TC} and
Nevirapine
{NVP} presented with fever, vomiting and pain in abdomen for 2 months. For these complaints, a USG abdomen was done that showed mild hepatomegaly with matted lobulated hypoechoiec mass in left lumbar region. CT abdomen also showed extensive mesenteric and periaortic lymphadenopathy suggestive of tuberculosis {TB}. She was started on antituberculous therapy {ATT} consisting of
Isoniazid
{H},
Rifampicin
{R},
Pyrazinamide
{Z} and
Ethambutol
{E} along with steroids. She underwent an abdominal lump biopsy and pus smear showed presence of 5 acid fast bacilli {AFB}. However her TB culture after 6 weeks showed no AFB. On follow up after 3 months of ATT, her lump size had regressed from 7 cm to 4.3. Her CD4 count was 64 {11 percent}.
Why did the TB culture not grow AFB_?
2
Expert Opinion :
We have also consudered that cultures did not grow as it may be very little bacterial load.
Answer Discussion :
S
shanthi shanthi
0
Report Spam
Could it be atypical mycobacteriae_?
13 years ago
A
akila devic
0
Report Spam
att started might have destroyed the bacilli
13 years ago
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Disease A-Z
Health Topics
Developmental Pediatrics
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