Skin TB with Vascular occlusion
Author:
Pediatric Oncall
Question
A 3 years old girl presented with hyper pigmented macules over left inguinal region. She was diagnosed to have cutaneous TB on skin biopsy and was on anti TB therapy for past 1 year. A repeat skin biopsy showed vascular occlusion but no granulomas. She was advised to do Protein S, Factor V Leiden, antiphospholipid antibodies_?
Why did this child have vascular occlusion_?
Expert Opinion :
Erythema induratum of bazin or nodular vasculitis. Histology should show three of four of the following elements: 1} septal panniculitis` 2} fat necrosis` 3} small or large vessel vasculitis` and 4} granulomas.