Skin TB with Vascular occlusion


A 3 years old girl presented with hyper pigmented macules over left inguinal region. She was diagnosed to have cutaneous TB on skin biopsy and was on anti TB therapy for past 1 year. A repeat skin biopsy showed vascular occlusion but no granulomas. She was advised to do Protein S, Factor V Leiden, antiphospholipid antibodies_?
Expert Opinion :
Erythema induratum of bazin or nodular vasculitis. Histology should show three of four of the following elements: 1} septal panniculitis` 2} fat necrosis` 3} small or large vessel vasculitis` and 4} granulomas.
Answer Discussion :
Abhay K Shah
Hyper coagulation state induced by mycobacterial products,which leads to activation of interleukin 6 and TNF
10 months ago
Eslam Aly
May have thrombophilia
10 months ago

View More Comments
ask doctor
Ask a Doctor
Disclaimer: The information given by is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.