Drug Index

Asenapine

 
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Mechanism :

Exact mechanism is unknown. May control psychotic symptoms through antagonism of selected dopamine and serotonin receptors in the CNS.


Indication :

• Bipolar disorder


Dosing :

Bipolar disorder, Acute manic or mixed episode; monotherapy:

Children ≥10 years and Adolescents ≤17 years: (Sublingual) Initial 2.5 mg twice daily; may double the dose every 3rd day to 10 mg twice daily.


Adverse Effect :

Somnolence, oral hypoesthesia, headache, dizziness, neuroleptic malignant syndrome tardive dyskinesia, hyperglycemia, diabetes mellitus, weight gain, orthostatic hypotension, syncope, leukopenia, neutropenia, QT interval prolongation, hyperprolactinemia, seizures, dysphagia.

07/17/2019 10:38:13 Asenapine
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