Drug Index


Mechanism :

It is an antiamoebic agent used in the treatment of intestinal and hepatic amoebiasis. It acts by inhibiting protein synthesis by arresting intra ribosomal translocation of tRNA-amino acid complex. Kills trophozoites but ineffective against cysts. It is available in both tablet and injectable preparations and is less toxic as compared to emetine.

Indication :

  • Acute amoebic dysentery
  • Amoebic liver abscess
  • Liver fluke infestation

Dosing :

0.75-1 mg/kg/day in 2 divided doses IM for 5 days.

Adverse Effect :

Nausea, vomiting, diarrhea, hypotension, myalgia, ECG changes and myocarditis.

Hepatic Dose :

No dosage adjustments are recommended.
01/21/2024 09:24:48 Dehydroemetine
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0