Drug Index

Inactivated Polio Vaccine

Synonym :

Injectable Polio Vaccine

Mechanism :

The vaccine is a highly purified, inactivated poliovirus vaccine with enhanced potency. Each of the three strains of poliovirus is individually grown in Vero cells, a continuous line of monkey kidney cells cultivated on microcarriers.

Indication :

  • Poliomyelitis prophylaxis

Contraindications :

Contraindicated in persons with a history of hypersensitivity to any component of the vaccine, including 2-phenoxyethanol, formaldehyde, neomycin, streptomycin and polymyxin B, if anaphylaxis or anaphylactic shock occurs within 24 hours of administration of one dose of vaccine. Vaccination of persons with an acute, febrile illness should be deferred until after recovery; however, minor illness, such as mild upper respiratory infection, with or without low grade fever, are not reasons for postponing vaccine administration.

Dosing :

IM or deep SC:
0.5 mL. First and second dose given 1-2 months apart at 2 and 4 months of life. The third dose is given after 18 months and the fourth dose at the age of 4-6 years.

Adverse Effect :

A mild local erythematous reaction or fever may occur. Irritability, tiredness and fever may be seen.

Interaction :

It can be given simultaneously with or at 4 weeks interval before or after, any other vaccine.

Hepatic Dose :

No dosage adjustments are recommended.
02/21/2024 22:48:27 Inactivated Polio Vaccine
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