Drug Index

Influenza Nasal Vaccine

 
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Mechanism :

Influenza Virus Vaccine Live, Intranasal is a live trivalent nasally administered vaccine intended for active immunization for the prevention of influenza.


Indication :

• Active immunization for the prevention of disease caused by influenza A and B viruses


Contraindications :

Under no circumstances should be administered parenterally. Individuals with a history of hypersensitivity, especially anaphylactic reactions, to any component, including eggs or egg products, should not receive Influenza Virus Vaccine Live, Intranasal. Contraindicated in children and adolescents receiving aspirin therapy or aspirin-containing therapy, because of the association of Reye syndrome with aspirin and wild-type influenza infection. Should not be administered to individuals who have a history of Guillain-Barré syndrome, to individuals with known or suspected immune deficiency diseases such as combined immunodeficiency, agammaglobulinemia, and thymic abnormalities and conditions such as human immunodeficiency virus infection, malignancy, leukemia, or lymphoma.


Dosing :

5-8 years: Not previously vaccinated: 2 doses (0.5 mL each, 60 days apart ± 14 days) for initial season; Previously vaccinated-1 dose (0.5 mL) per season.

9-49 years: 1 dose (0.5 mL) per season.


Adverse Effect :

Runny nose/nasal congestion, sore throat, cough, irritability, headache, chills, vomiting, muscle aches, and decreased activity and a feeling of tiredness/weakness.


Interaction :

Aspirin: Children or adolescents who are receiving aspirin therapy or aspirin-containing therapy should not receive Influenza Virus Vaccine Live, Intranasal. The concurrent use with antiviral compounds that are active against influenza A and/or B viruses has not been evaluated. However, it is advisable not to administer Influenza Virus Vaccine Live, Intranasal until 48 hours after the cessation of antiviral therapy.


07/19/2019 04:05:20 Influenza Nasal Vaccine
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