Drug Index


Mechanism :

Lindane is a parasiticidal agent used in the treatment of head lice and scabies. It has also been used to control disease-causing vectors such as mosquitoes.

Indication :

  • Non-crusted scabies
  • Head lice or crab lice
  • Pediculosis capitis
  • Pediculosis pubis

Contraindications :

Hypersensitivity to drug/class/component.

Seizure disorder, Norwegian (crusted) scabies, Premature neonates, Lindane use history.

Caution in infants or children, head injury, HIV infection or CNS tumor.

Dosing :

Scabies, Pediculosis capitis, Pediculosis pubis:
Apply 1% lotion once (Max: 15 mL in children between 1 month-6 years and 30 ml in children above 6 years of age). Do not apply on open wounds.
Head lice or Crab lice:
Apply 1-2 ounces of shampoo on dry hair for four minutes followed by lathering, rinsing and removal of nits with a fine comb.

Adverse Effect :

Seizure, slight local irritation (including eczematous eruptions, rash, conjunctivitis), cardiac arrhythmia, restlessness, nausea/vomiting, seizures, pulmonary edema, alopecia, repeated application frequently causes contact dermatitis, aplastic anemia, ataxia, pain, dizziness, urticaria, hepatitis, hematuria, paresthesia.

Interaction :

Monitor/Modify Treatment:
Magnesium citrate.
Caution Advised:
Aminophylline, Amitriptyline, Amoxapine, Amoxicillin, Amphetamine, Ampicillin, Aripiprazole, Asenapine, Baclofen, Baclofen Intrathecal, Benzphetamine, Buprenorphine, Bupropion, Busulfan, Butorphanol, Butorphanol Nasal, Chloroquine, Chlorpromazine, Ciprofloxacin, Clomipramine, Clozapine, Cyclobenzaprine, Cyclosporine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextroamphetamine, Dicloxacillin, Diethylpropion, Donepezil, Doxepin, Edrophonium, Enzalutamide, Fluphenazine, Galantamine, Gemifloxacin, Haloperidol, Iloperidone, Imipenem, Imipramine, Isocarboxazid, Isoniazid, Levocarnitine, Levofloxacin, Linezolid, Lisdexamfetamine, Loxapine, Lurasidone, Maprotiline, Meperidine, Methamphetamine, Methocarbamol, Methylphenidate, Metronidazole, Milnacipran, Mirtazapine, Moxifloxacin, Nafcillin, Nalbuphine, Nefazodone, Neostigmine, Norfloxacin, Nortriptyline, Ofloxacin, Olanzapine, Oxacillin, Paliperidone, Penicillin G, Penicillin V, Pentazocine, Perphenazine, Phendimetrazine, Phenelzine, Phentermine, Physostigmine, Pimozide, Piperacillin, Procarbazine, Prochlorperazine, Promethazine, Protriptyline, Pyridostigmine, Pyrimethamine, Quetiapine, Rasagiline, Risperidone, Rivastigmine, Selegiline, Selegiline Transdermal, Sodium phosphate (bowel prep), Sodium phosphate rectal, Sulfate bowel prep, Tacrine, Tacrolimus, Tapentadol, Theophylline, Thioridazine, Thiothixene, Tiagabine, Ticarcillin, Tramadol, Tranylcypromine, Trazodone, Trifluoperazine, Trimipramine, Venlafaxine, Ziprasidone.

Hepatic Dose :

If systemically absorbed, metabolism of lindane may be impaired in patients with severe hepatic disease and may lead to neurotoxicity.
03/24/2024 11:56:54 Lindane
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