Drug Index

Pneumococcal Polysaccharide Vaccine

Mechanism :

Pneumococcal polysaccharide vaccine, Pneumo 23 is a capsular polysaccharide vaccine against disease caused by 23 of the most common types of S. pneumoniae (pneumococcus).

Indication :

  • Pneumococcal invasive disease prophylaxis
  • Recurrent otitis media
  • Asplenia- functional
  • Sickle cell disease
  • Celiac disease
  • Splenectomy - prior to elective splenectomy
  • Chronic renal disease
  • Nephrotic syndrome
  • Immunodeficiency
  • Immunosuppression
  • AIDS/HIV Infection
  • Chronic heart disease
  • Cyanotic heart disease
  • Juvenile diabetes mellitus
  • Chronic liver disease
  • Severe asthma
  • Cochlear Implant

Contraindications :

Immunization with the pneumococcal polysaccharide vaccine, should be deferred in the presence of any acute illness, including febrile illness. A minor afebrile illness such as mild upper respiratory infection is not usually reason to defer immunization. Absolute Contraindications: Allergy to any component of the pneumococcal polysaccharide vaccine or an allergic or anaphylactic reaction to a previous dose of pneumococcal vaccine are contraindications to vaccination.

Immunization is contraindicated in persons who were given a pneumococcal vaccine within the previous 3 years.

Dosing :

Deep SC or IM: 0.5 ml as single dose in children more than 2 years of age. Booster doses of the plain polysaccharide vaccine are not normally recommended and should certainly not take place within 3 years of the first dose as marked local reactions can occur. As the vaccine is likely to be used in conjunction with the conjugate vaccine in children, it is not known whether boosters will be required.

Adverse Effect :

Local reactions at the injection site including pain, erythema, and induration occur. These reactions are generally mild and transient. Rarely, Arthus-like reactions have been reported. These occur mainly in persons with high pneumococcal antibody levels.

Systemic Reactions: Febrile episodes occur early after vaccination and generally resolve within 24 hours, and headache and/or general malaise may occur.

Allergic-type reactions including urticaria, angioedema and anaphylaxis have been reported.

Interaction :

Vaccines: It can be given simultaneously with, or 4 weeks before or after any other vaccine.

Hepatic Dose :

No dosage adjustments are recommended.
02/19/2024 23:08:22 Pneumococcal Polysaccharide Vaccine
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0