Pyrantel Pamoate
Mechanism :
It is an anthelmintic drug used in treatment of worm infestations like hookworm, roundworm, threadworm and pinworm. It causes paralysis of the worms and expulsion of the worms.
Indication :
- Enterobiasis
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Contraindications :
Allergic to any ingredient in pyrantel pamoate
Liver problems
Dosing :
Enterobiasis, Ascariasis, Trichostrongylosis, Moniliformis Infection:
≥2 years:
11 mg/kg base (Maximum 1 g) once daily. Repeat dose in 2 weeks for Enterobiasis. Repeat dose twice at 2 weeks intervals for Moniliformis Infection.
Hookworm Infection (Necator or Ancylostoma):
≥2 years:
11 mg/kg base (Maximum 1 g) orally daily for 3 days.
Adverse Effect :
Headache, dizziness and other GI disturbances.
Interaction :
ARI Sodium Iodide (I123) 1-12 MBq (sodium iodide i-123) ARI
Sodium Iodide (I123) 100-750 MBq (sodium iodide i-123)
Hicon (sodium iodide-i-131)
Iodotope (sodium iodide-i-131)
Sodium iodide i-123 sodium iodide-i-131
Hepatic Dose :
Dose adjustment may be required, use with caution.