ISSN - 0973-0958

Pediatric Oncall Journal View Article

Refractory Ulcerative Colitis in a Toddler and response to Infliximab - A Case Report and Review of Literature
Himali Meshram.
Pediatric Gastroenterology and Hepatology unit, Apollo Clinics, Nagpur, Maharashtra, India.
Abstract
Ulcerative Colitis (UC) in younger age group has poor response to medical line of management and surgical treatment is more successful. Here we present a 2-year-old boy who had recurrent diarrhea with failure to thrive from first week of life. He was detected to have UC on colonic biopsy and histopathology with a high stool calprotectin (425.9 ug/g). He was started on oral prednisolone and sulfasalazine but due to poor response, was subsequently treated with infliximab and azathioprine to which he responded with a fall in stool calprotectin (28 ug/g) and weight gain of 2.9 kg in 4 months.

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