Successful outcome of rhino-orbital mucormycosis in a case of type i diabetes mellitus

Year: October-December 2006 | Volume: 3 | Issue: 4 | Pages: 66-67

CASE REPORTS

SUCCESSFUL OUTCOME OF RHINO-ORBITAL MUCORMYCOSIS IN A CASE OF TYPE I DIABETES MELLITUS

MR Wade¹, AR Jadhav¹, RA Bradoo², MV Manglani¹.
¹Department of Pediatrics, Lokmanya Tilak Municipal Medical College & General Hospital, Sion, Mumbai 400 022, India,
²Department of ENT, Lokmanya Tilak Municipal Medical College & General Hospital, Sion, Mumbai 400 022, India.

Abstract
Mucormycosis is a rare and life threatening fungal infection in children that occurs in association with immunocompromised states. Very few case reports of rhino-orbital mucormycosis have been documented in pediatric age group and most of these have been fatal. We report a case of mucormycosis in a child with type I Diabetes Mellitus who presented with sero-sanginous nasal discharge along with orbital cellulitis. Nasal mucosal biopsy revealed aseptate hyphae diagnostic of mucormycosis. The CT showed involvement of ethmoid and maxillary sinuses along with retro-orbital extension, sparing cerebral involvement. We managed the child with lipid complex amphotericin B coupled with repeated surgical debridement. On follow up at six months, the child was disease free.

Key Messages:

Mucormycosis is a rare but an acute and frequently fatal infection in young patients with type 1 diabetes mellitus.

High index of suspicion and combined approach with amphotericin B and appropriate surgery is rewarding in management of mucormycosis.

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Wade M, Jadhav A, Bradoo R, Manglani M. SUCCESSFUL OUTCOME OF RHINO-ORBITAL MUCORMYCOSIS IN A CASE OF TYPE I DIABETES MELLITUS. Pediatr Oncall J. 2006;3: 66-67.