Neonatal Cholestasis
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Neonatal Cholestasis
30/06/2014
30/06/2014
Ira Shah
https://www.pediatriconcall.com/Journal/images/journal_cover.jpg
Dr Ira Shah.
Medical Sciences Department, Pediatric Oncall, Mumbai, India.
ADDRESS FOR CORRESPONDENCE
Dr Ira Shah, 1, B Saguna, 271, B St Francis Road, Vile Parle {W}, Mumbai 400056 |
Clinical Problem
An 8 months old boy born of non consanguineous marriage presented with jaundice, yellow urine and clay stools since day 6 of life. On examination, he had rickets, weight was 6.2 kg, He had jaundice with hepatosplenomegaly. His liver biopsy was suggestive of biliary atresia.
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How to take care of his nutrition and deficiency of fat soluble vitamins_?
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Discussion
Since Vitamins A, D, E and K are fat soluble vitamins and require bile for absorption, in case of biliary atresia, due to cholestasis, bile is not secreted into the intestines and thus there is malabsorption of fat soluble vitamins. Thus, these vitamin deficiencies can occur. Supplementation of these vitamins in 10 times recommended daily allowance is thus needed. Water soluble forms of these vitamins should be administered orally so that absorption in absence of bile is not hampered. Regarding nutrition, since bile excretion is poor, even fats are not absorbed. Only medium chain triglycerides {MCT} are absorbed. Thus supplements with MCT oil is required. Adequate calorie and protein intake should be taken care of so that nutrition requirements are met.
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| Compliance with ethical standards |
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Funding: None
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Conflict of Interest: None
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Cite this article as:
Shah I. Neonatal Cholestasis. Pediatr Oncall J. 2014;11: 95. doi: 10.7199/ped.oncall.2014.51
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