Case Report: - A 10 years old boy presented with reddish rash with lip edema and prepucial edema on and off for the past 2 years. On examination there is no significant finding. There is no exposure to any particular allergen. On investigation:
· Hemoglobin = 11 gm/dl
· WBC count = 11,000/cumm [polymorphs 40%, lymphocytes 58%, eosinophils 2%]
· ESR = 20 mm at end of 1 hour
· C3 = 150 mg/dl (Normal = 90-120 mg/dl)
· ANA = Negative