Treatment of hypercalcemia consists of
• Hydration with diuresis
• IV Pamidronate
• Steroids if hypercalcemia is due to 1, 25 dihydroxy Vitamin D overproduction.
The initial step would be to give 1½ times to twice the maintenance fluids followed by
Furosemide to cause loss of calcium in the urine. If that does not resolve the hypercalcemia, then IV
Pamidronate (bisphosphonates) are useful to suppress osteoclastic activity and thus prevent resorption of calcium from the bones.
An oral short course of steroids may be useful to decrease intestinal absorption of calcium in cases of hypervitaminosis D. The goal of therapy is to normalize ionic calcium levels to prevent sudden cardiac arrhythmias.