Drug Index


Synonym :

Aluminium Magnesium Hydroxide

Mechanism :

It is an antacid that is a combination of magnesium and aluminium hydroxide.

Indication :

  • Esophagitis
  • Gastroesophageal reflux
  • Gastric ulcer
  • Duodenal ulcer
  • Hiatal hernia
  • Stomach upset
  • Hyperphosphatemia
  • Magnesium deficiency.

Contraindications :

Hypersensitivity, renal disease, Mg-restricted diet, while taking citrate salts found in calcium supplements, antacids and laxatives.

Dosing :

Safety and efficacy not established in children.
Adult dose:
1-2 tsf after meals and at bedtime.

Adverse Effect :

Magnesium salt may cause diarrhea and aluminium salt (10%) may cause constipation and chalky taste. Intestinal pain, black tarry stools, coffee ground vomitus, dark urine, allergic manifestations are seen with the suspension. Others: osteomalacia, bone pain, muscular weakness, malaise, decreased fluoride absorption, milk-alkali syndrome, and aluminium accumulation in serum, bone and the CNS, rebound hyperacidity, hypophosphatemia and hypermagnesemia.

Interaction :

Sodium Polystyrene Sulphonate, Dolutegravir, Iron, Tetracycline, Benzodiazepines, Indomethacin, Oral Antidiabetic Medication, Digoxin: Magaldrate interacts strongly.

Antacid: Avoid taking any medication within 1 to 2 hours of taking an antacid. The antacid may interfere with the absorption of the medication.

Hepatic Dose :

No dosage adjustments are recommended. Avoid in hepatic coma if risk of renal failure.
03/23/2024 03:58:43 Magaldrate
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