Drug Index

Magaldrate

 
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Synonym :

Aluminium Magnesium Hydroxide

Mechanism :

It is an antacid that is a combination of magnesium and aluminium hydroxide.


Indication :

• Esophagitis

• Gastroesophageal reflux

• Gastric ulcer

• Duodenal ulcer

• Hiatal hernia

• Stomach upset

• Hyperphosphatemia

• Magnesium deficiency.


Contraindications :

Hypersensitivity, renal disease, Mg-restricted diet, while taking citrate salts found in calcium supplements, antacids and laxatives.


Dosing :

Safety and efficacy not established in children.

Adult dose: 1-2 tsf after meals and at bedtime.


Adverse Effect :

Magnesium salt may cause diarrhea and aluminium salt (10%) may cause constipation and chalky taste. Intestinal pain, black tarry stools, coffee ground vomitus, dark urine, allergic manifestations are seen with the suspension. Others: osteomalacia, bone pain, muscular weakness, malaise, decreased fluoride absorption, milk-alkali syndrome, and aluminium accumulation in serum, bone and the CNS, rebound hyperacidity, hypophosphatemia and hypermagnesemia.


Interaction :

Sodium Polystyrene Sulphonate, Dolutegravir, Iron, Tetracycline, Benzodiazepines, Indomethacin, Oral Antidiabetic Medication, Digoxin: Magaldrate interacts strongly.

Antacid: Avoid taking any medication within 1 to 2 hours of taking an antacid. The antacid may interfere with the absorption of the medication.


07/17/2019 10:28:54 Magaldrate
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