ISSN - 0973-0958

Pediatric Oncall Journal View Article

Status Epilepticus and Metabolic Acidosis in Isoniazid toxicity
Rajniti Prasad1,2, Biswanath Basu1,2, Om Prakash Mishra1,2, Utpal Kant Singh1,2.
1Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi,
2Department of Pediatrics, Nalanda Medical College, Patna, India.
A four year child with history of accidental ingestion of 13 tablets isoniazid-rifampicin i.e. 1.3 gm of isoniazid presented with status of generalized tonic-clonic seizure and fast breathing. The child did not respond to lorazepam, phenytoin and phenobarbitone but responded only after giving intravenous pyridoxine therapy and correction of acidosis.

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