Q. A 28-day-old neonate weighing 3 kg at present came with a history of seizures on 22 day of his life with bruising and petechial rash over the body. There was hepatomegaly, but the consistency was soft. The neonate was dull and lethargic with poor neonatal reflexes. Ser sodium was 132 and pott was 5.2, LFT was normal except for the raised GGT to 2000. The CECT was normal except for the leptomeningeal enhancement.CSF showed a raised protein of 300 and low sugar of 28{blood sugar -80} and a few degenerated cells{had received antibiotics for 6 days outside}.IV antibiotics were started in meningitic doses. The neonate has started improving. Platelets have improved. required a blood transfusion in view of low Hb of 7 gm percent. Serum
Albumin was low. Urea and creatinine were within normal range. Electrolytes are presently within normal range. Presently on
Phenobarbitone and IV antibiotics and feeds are going and; neurologically, the neonate has improved.
But the concern is that the neonate does not pass adequate urine and does so only after he is given Lasix. Would it be wise to give Lasix, although renal parameters and electrolytes are normal?
What could be the reason for raised GGT?