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Posted On : 31 Aug 2025

A newborn came on D14, his weight is 2.0 Kg, Full Term, TSB-15.2, DIRECT-2.8, septic screen negative, blood group-B+, Mother blood Grp O+, sgot sgpt around 480, baby is active feeding normally. How should I approach this now? What is the role of Photo therapy at this stage?

Expert Answer :

Answer Discussion :

H

Hafiz Akhtar

0

Babies remain well unless their neurological and hamodynamic status is not compromised so don,t go on the well-being of baby. It is a complex situation needing aggressive approach to reach the accurate diagnosis.
RED FLAGS in this case are 1: Hyperbilirubinaemea with LBW,2:ABO Incompatiblity and hepatic injury (post Cholistatic)
IMMEDIATE ACTION should be 1: Admission in NICU With co-ordinated management by Neonatologist and paediatric Gastroenterologist/Hepatologist.
IMMEDIATE WORKUP FOR,
Infectious, Genetic/Metabolic, Structural(biliary atresia) defects and Idiopathic Neonatal Hepatitis is required. Alpha-1 Antitrypsin deficiency must also be considered.In neonates UTI may also present with cholistates and increased Liver enzymes
IMMEDIATE TREATMENT FOR,
1:Hyperbilirubinaemea (indirect)as baby is 2 kg —phototherapy 2: Hydration & Nutrition and 3: Treatment of cause.

23 Days ago

M

Manar Aref

0

prolonged neonatal jaundice, increased DSB goes with cholestasis. what about CBC especially Hb level bec risk of Inspissated bile syndrome is possible, do urine analysis bec some cases with UTI has prolonged jaundice,
is stool colour clay ?? this is important to exclude biliary atresia

25 Days ago

S

Shilpa Rahamatkar

0

D14..... TSB 15.2....needs phototherapy.....rule out probable ABO incompatibility ....liver enzymes too raised ....needs more inv ...

25 Days ago

A

Abdo Free

0

request coomb,s test firstly to exclude aiha

25 Days ago

I