Question of the Week

Question :
Posted On : 27 Apr 2025
Why the dose of Piperacillin alone is 100 mg/kg and the dose of Piperacillin with tazobactam 300-400mg/kg?
3
Expert Answer :
Piperacillin dose is Neonates Less than 7 days: 150 mg/kg/day IM, IV in 3 divided doses, neonates More than 7 days: 200 mg/kg/day IM, IV in 4 divided doses. Infants and children: 200-300 mg/kg/day IV/IM in divided doses q 4-6. (Max 24g/day)

For Piperacillin tazobactum
Dosing is based on the Piperacillin component.
Infants Less than 6 months: 150 – 300 mg/kg/day IV in 3-4 divided doses, infants More than 6 months and children: 240 mg/kg/day IV in 3 divided doses. For serious pseudomonal infections dose of 300-400 mg/kg/day in 4 divided doses has been used (max 18 g Piperacillin component, day)
Answer Discussion :
G
Gladys Yonah
Profile
the 200mg is added for tazobactam
6 Days ago
T
Tanveer Ahmad
Profile
don't know why
6 Days ago
B
Bushra Khaan
Profile
Because tazobactam increases its clearance
6 Days ago




Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0