ISHAK scoring on liver histopathology

Periportal or periseptal interface hepatitis (piecemeal necrosis)




Confluent necrosis






Focal (spotty) lytic necrosis, apoptosis and focal inflammation




Portal inflammation




Result :
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References :

    Zeuzem S, Feinman SV, Rasenack J, Heathcote EJ, Lai MY, Gane E, et al. Peginterferon alfa-2a in patients with chronic hepatitis C. N Engl J Med 2000;343:1666–1672.

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