Modified Leipzig Score

Kayser-Fleischer rings

Serum ceruloplasmin



24-h urinary copper (in the absence of acute hepatitis)


Coomb's-negative hemolytic anemia with liver disease

Mutational analysis


Liver biopsy for histology suggestive of WD

Neurobehavioral symptoms

Typical features on MRI brain

History of Wilson disease in a family member

Result :
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References

Nagral A, Sarma MS, Matthai J, Kukkle PL, Devarbhavi H, Sinha S, Alam S, Bavdekar A, Dhiman RK, Eapen CE, Goyal V, Mohan N, Kandadai RM, Sathiyasekaran M, Poddar U, Sibal A, Sankaranarayanan S, Srivastava A, Thapa BR, Wadia PM, Yachha SK, Dhawan A. Wilson's Disease: Clinical Practice Guidelines of the Indian National Association for Study of the Liver, the Indian Society of Pediatric Gastroenterology, Hepatology and Nutrition, and the Movement Disorders Society of India. J Clin Exp Hepatol. 2019 Jan-Feb;9(1):74-98. doi: 10.1016/j.jceh.2018.08.009. Epub 2018 Sep 3. Erratum in: J Clin Exp Hepatol. 2020 Jan-Feb;10(1):99. PMID: 30765941; PMCID: PMC6363961.

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