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METABOLIC LIVER DISEASE
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Nafld (non-alcoholic fatty liver disease) activity score
NAFLD (Non-Alcoholic Fatty Liver Disease) Activity Score
Steatosis grade
Low- to medium-power evaluation of parenchymal involvement by steatosis
<5%
5-33%
34-66%
>66%
Lobular inflammation
Overall assessment of all inflammatory foci
No foci
1 focus per 200× field
2‐4 foci per 200× field
>4 foci per 200× field
Liver cell injury
Ballooning
None
Few balloon cells
Many cells/prominent ballooning
Result :
Please fill out required fields.
Please fill out required fields.
Interpretation
Score
Diagnosis
0–2
Not steatohepatitis
3-4
Indeterminate
≥5
Steatohepatitis
Instructions
Use in patients who have had liver biopsy for NAFLD.
References
Kleiner DE, Brunt EM, Van natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41(6):1313-21.
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Disease A-Z
Health Topics
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
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Nutrition
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View all topics
Featured Articles
Diabetic ketoacidosis
Anaphylaxis
Anal itching
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Penile hygiene
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