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METABOLIC LIVER DISEASE
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Nafld (non-alcoholic fatty liver disease) activity score
NAFLD (Non-Alcoholic Fatty Liver Disease) Activity Score
Steatosis grade
Low- to medium-power evaluation of parenchymal involvement by steatosis
<5%
5-33%
34-66%
>66%
Lobular inflammation
Overall assessment of all inflammatory foci
No foci
1 focus per 200× field
2‐4 foci per 200× field
>4 foci per 200× field
Liver cell injury
Ballooning
None
Few balloon cells
Many cells/prominent ballooning
Result :
Please fill out required fields.
Please fill out required fields.
Interpretation
Score
Diagnosis
0–2
Not steatohepatitis
3-4
Indeterminate
≥5
Steatohepatitis
Instructions
Use in patients who have had liver biopsy for NAFLD.
References
Kleiner DE, Brunt EM, Van natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41(6):1313-21.
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Disease A-Z
Health Topics
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
Pediatric Dermatology
View all topics
Featured Articles
Penile hygiene
Anal fissure
Anaphylaxis
Hypospadias
Urticaria (hives) and angioedema
Circumcision
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