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DENGUE ALONG WITH PORTAL HYPERTENSION
Author:
Pediatric Oncall
Question
A 5 years old boy with congenital temporo-mandibular joint ankylosis was operated for same following which he developed fever 8 days post-operatively with 2 episodes of hematemesis. There was no jaundice or bleeding from any other site in the past. On examination heart rate was 120, min, respiratory rate was 30, min and blood pressure was 90, 60 min of Hg. There was no icterus. He had splenomegaly and other systems were normal. Investigations showed hemoglobin of 10.3 gm, dl, WBC count of 4,400, cumm and platelets of 1,16,000, cumm with bilirubin of 10.7 mg, dl, SGOT of 72 IU, L and SGPT of 145 IU, L. His prothrombin time was 15.2 sec and partial thromboplastin time was More than 2 mins and serum
Albumin
was 2.8 gm, dl. Ultrasound abdomen with colour doppler showed mild hepatomegaly with altered echotexture and few intrahepatic and peri-gallbladder varices. HBsAg, Hepatitis A antibody and hepatitis E antibody were negative. Dengue IgM was positive. His CT angiography showed replacement of portal and splenic vein with numerous collaterals. He was treated with fresh frozen plasma, vitamin K,
Vasopressin
and antacids but his hematemesis persisted. Esophageogastroscopy was not possible due to surgery on temporo-mandibular joint.
How to control the hematemesis in this child_?
2
Expert Opinion :
Though the child had portal hypertension, his episode of hematemesis also coincided with acute dengue infection. Thus apart from portal hypertension, bleeding could also be related to coagulopathy and thrombocytopenia due to dengue. This child thus was additionally given platelet and
FFP
transfusion and his hematemesis subsided. He then underwent Esophageogastroscopy after one month of surgery.
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Disease A-Z
Health Topics
Developmental Pediatrics
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