Melioidosis in children from southern coastal india

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Melioidosis in Children from Southern Coastal India

Shravan Kanaparthi, Suneel C Mundkur, Kalyan Chakravarthy Konda, Shrikiran Aroor, Ujjwala Mantha.

Department of Paediatrics, Kasturba Medical College, Manipal, Manipal University, Karnataka, India.

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Abstract
Melioidosis is an infectious disease caused by a gram-negative bacillus, Burkholderia pseudomallei. It is known to be endemic in Southeast Asia and Northern Australia. There is a recent surge in cases from coastal India. We hereby report four episodes of Melioidosis in 3 children with one child having a recurrent episode. One child was male and two were female, with all the children aged more than ten years (range 10-14years). Fever was the most common symptom followed by abdominal and bone pain in 50% of episodes. Immunocompromised state (post-splenectomy status and steroid therapy) as a predisposing factor was present in 2 children. One child presented with septicemia and succumbed within 72 hours of admission. Ceftazidime/Meropenem and cotrimoxazole were used in intensive and eradication phase respectively. A comprehensive knowledge and high index of suspicion are required to diagnose Melioidosis. Prolonged treatment course with appropriate antibiotics would help in minimizing the mortality and morbidity in children.

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