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Expert Opinion
Q.
Why the dose of piperacillin alone is 100 mg/kg and the dose of piperacillin with tazobactam 300-400mg/kg?
Post Date :
27 Apr 2025
Expert Opinion:
Piperacillin dose is Neonates Less than 7 days: 150 mg/kg/day IM, IV in 3 divided doses, neonates More than 7 days: 200 mg/kg/day IM, IV in 4 divided doses. Infants and children: 200-300 mg/kg/day IV/IM in divided doses q 4-6. (Max 24g/day)
For piperacillin tazobactum
Dosing is based on the piperacillin component.
Infants Less than 6 months: 150 – 300 mg/kg/day IV in 3-4 divided doses, infants More than 6 months and children: 240 mg/kg/day IV in 3 divided doses. For serious pseudomonal infections dose of 300-400 mg/kg/day in 4 divided doses has been used (max 18 g piperacillin component, day)
Q.
How much dilution of ceftriaxone and mikacin is recommended? We are giving ceftriaxone 1 gm in 100 ml ns. Can we give it in routine RL or DNS or isolyte p 500 ml drip? We are giving Mikacin without dilution. What are your recommendations?
Post Date :
20 Apr 2025
Expert Opinion:
Do not use diluents containing calcium, such as Ringer’s solution or Hartmann’s solution, to reconstitute ceftriaxone. It should be administered intravenously by infusion over a period of 30 minutes. Concentrations between 10 mg/mL and 40 mg/mL are recommended. It is stable for 24 hours at room temperature only in 0.9 percent sodium chloride injection or 5 percent dextrose in water (D5W).
Usual diluent for amikacin is NS, D5W. Amikacin sulfate is stable for 24 hours at room temperature and 2 days at refrigeration at concentrations of 0.25 and 5.0 mg, mL in the following solutions:
5% Dextrose Injection, USP
5% Dextrose and 0.2 percent Sodium Chloride Injection, USP
5% Dextrose and 0.45 percent Sodium Chloride Injection, USP
0.9% Sodium Chloride Injection, USP
Lactated Ringer’s Injection, USP
Q.
What is the correct way of nebulization. Should we use the medicine with saline or only with that medicine?
Post Date :
13 Apr 2025
Expert Opinion:
Depending if you use respule or nebulizing solution, Respules do not need to be diluted. Nebulising solutions need to be given in NS.
Q.
Female age 9-year good behavior, and is active, she is the second child, and she has 2 brothers and .......
Post Date :
06 Apr 2025
Expert Opinion:
Since it is secondary nocturnal enuresis, rule out urine infection, diabetes mellitus, diabetes insipidus, RTA and emotional disturbances.
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Disease A-Z
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