Drug Index

Framycetin Sulphate

Mechanism :

It is a topical aminoglycoside. Framycetin works by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth.

Indication :

  • Bacterial conjunctivitis, bacterial blepharitis, corneal ulcers, corneal injuries.
  • Prophylaxis of ocular infections following foreign body removal.
  • ENT infections and burns and scalds.
  • Otitis externa

Contraindications :


Framycetin Sulphate is contraindicated in conditions like Tuberculosis, Viral eye infection, Glaucoma.

Dosing :

Available as ophthalmic solution and cream.
Ophthalmic/Otic drop:
1-2 drops 3-4 times daily. Ointment: Application at bedtime.

Adverse Effect :

Inflammation, irritation, contact dermatitis, burning sensation, stinging, pruritus, ototoxicity, GI symptoms.

Hepatic Dose :

No dosage adjustments are recommended.
03/13/2024 06:01:08 Framycetin Sulphate
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