Drug Index

Ciclopirox

 
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Mechanism :

Ciclopirox is a synthetic broad-spectrum antifungal agent that inhibits the growth of pathogenic dermatophytes, yeasts, and M. furfur. It exhibits fungicidal activity in vitro against isolates of T. rubrum, T. mentagrophytes, E. floccosum, M. canis and C. albicans. It is presumed that ciclopirox mediated growth inhibition or death of fungal cells is primarily caused by in vitro cellular depletion of some essential substrates and/or ions and that such effects are brought about through blockage of their uptake from the medium.


Indication :

For the topical treatment of:

• Tinea pedis, tinea cruris and tinea corporis due to T. rubrum

• T. mentagrophytes

• E. floccosum

• M. canis

• Cutaneous candidiasis (moniliasis) due to C. albicans

• Tinea (pityriasis) versicolor due to M. furfur


Contraindications :

In individuals who have shown hypersensitivity to any of the product components.


Dosing :

Available as 0.77% is supplied in 15 gm cream. To be used in children 10 years and above.

Apply to affected areas twice daily for 4 weeks.


Adverse Effect :

Pruritis.


Interaction :

No known interactions found.


07/19/2019 03:10:29 Ciclopirox
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