Drug Index



Mechanism :

It is an anti-histaminic drug used as an anti-emetic. It has lesser antimuscarinic and lesser sedating properties. It is used to prevent and treat nausea and vomiting associated with motion sickness, Meniere’s disease, sea sickness, vertigo and chronic labyrinthitis.

Indication :

• Nausea/vomiting

• Vertigo

• Motion Sickness

Contraindications :

Renal impairment, Hepatic impairment, IOP increased, Glaucoma, COPD asthma, PUD, Hyperthyroidism, Hypertension, Lower resp. tract SX, GI obstruction, Prostatic hypertrophy, Bladder neck obstruction, High environmental temperature.

Dosing :

>12 years: 25 mg orally 1 to 4 times a day or 50 mg orally twice a day. Meclizine should be administered one hour prior to travel and continued for the duration of exposure.

Adverse Effect :

Dry mouth, thickened bronchial secretions, constipation, GI upset, urinary retention, drowsiness, Rare: anaphylaxis/anaphylactoid reaction, hemolytic anemia, thrombocytopenia, agranulocytosis, pancytopenia, leukopenia, arrhythmias, seizures, blurred vision, diplopia, tachycardia, photosensitivity, palpitations, diaphoresis, rash, difficulty swallowing, hives.

Interaction :


Cinacalcet; Quinidine; Terbinafine; the Antidepressants Bupropion, Duloxetine, Fluoxetine, Paroxetine, or Sertraline.

Hepatic Dose :

No dosage adjustments are recommended.
07/28/2020 02:32:18 Meclizine
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0