Drug Index



Mechanism :

Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution. Promethazine is an H1 receptor blocking agent. In addition to its antihistaminic action, it provides clinically useful sedative and antiemetic effects.

Indication :

• Sedation

• Antihistamine

• Nausea and vomiting

• Motion sickness

Contraindications :

Sensitivity to any of the components, patients receiving MAO inhibitors. Not recommended for children below 2 years of age.

Dosing :

<2 years, safety and efficacy not established.

>2 years: 0.25-1 mg/kg PO/PR every 4-6 hours as and when required; Maximum dose: 25 mg/day.

Adverse Effect :

Dryness of the mouth, blurring of vision, dizziness or mild stimulation and insomnia may occur. Rare: leukopenia.

Interaction :

Potentials sedative effects of other drugs; avoid alcohol.

03/10/2020 18:00:33 Promethazine
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0