Drug Index

Olopatadine

 
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Mechanism :

Olopatadine is a selective histamine H1 antagonist that binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Olopatadine is devoid of effects on alpha-adrenergic, dopamine and muscarinic type 1 and 2 receptors.


Indication :

• Allergic conjunctivitis

• Seasonal allergic rhinitis


Contraindications :

Hypersensitivity.


Dosing :

2 years or younger: Safety and effectiveness have not been established.

Allergic conjunctivitis:

3 to 18 years: Ophthalmic 0.1% solution: Instil one drop in each affected eye two times a day at a 6 to 8 hour interval. Ophthalmic 0.2% or 0.7% solution: Instil one drop in each affected eye once a day.

Seasonal allergic rhinitis:

6-12 years: 1 spray (0.6%) in each nostril twice a day.

>12 years: 2 sprays (0.6%) in each nostril twice a day.


Adverse Effect :

Burning, dry eyes, headache, blurred vision, asthenia, foreign body sensation, hyperemia, keratitis, eyelid edema, pharyngitis, rhinitis, sinusitis, taste perversion, nausea, pruritus, bitter taste, respiratory epistaxis after intranasal spray.


Interaction :

None.


08/06/2019 12:28:47 Olopatadine
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