Non-Tubercular Mycobacterial (NTM) Infections in Children; One Game, Many Players Case series from a Tertiary Pediatric Centre
Vandana Bharadwaj, Indumathi Chikkanayakanahalli.
Department of Paediatrics, St John’s Medical College & Hospital, Bengaluru, Karnataka, India.
Abstract
Non-Tubercular Mycobacterial (NTM) infection is rare in children. As Interleukin–12 interferon gamma (IL-12/IFN-γ ) axis plays an important role in conferring immunity to mycobacterial infections, its disorders have been increasingly reported in association with disseminated NTM and Bacillus Calmette Guerin (BCG) infections, known as Mendelian Susceptibility to Mycobacterial Diseases (MSMD). NTM infection occurs infrequently in patients with hematological malignancies undergoing chemotherapy. They have also been implicated in infections following intramuscular injections, laparoscopic and bronchoscopy procedures. We report a series of NTM infections in children with diverse aetiology, treated at a tertiary paediatric centre.

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