Drug Index

Methyl Salicylate

Synonym :


Mechanism :

Methyl Salicylate acts a counter rubefacient. It acts by stimulating the superficial afferent nerves from the same spinal segment that supplies the underlying painful muscles. The stimulation of these nerves causes vasodilation in that spinal segment and that reduces the cause of pain in the deeper muscles.

Indication :

  • Methyl salicylate is used as a topical preparation for the skin for temporary relief of muscle pain or joint pain caused by sprains, strains, arthritis, backaches or bruising.

Contraindications :

Hypersensitivity, ASA or NSAID-induced asthma or urticaria, Aspirin triad, Influenza, varicella, or febrile viral infection.

Caution if asthma and nasal polyps.

Dosing :

Available as 10% w/w.
>12 years:
Apply liberal amount topically to affected area and massage; Max: 4 times/day.

Adverse Effect :

Swelling, tingling sensation of skin, and blistering of the skin leading to severe burning pain wherever the medication is applied. A mild cold or burning sensation occurs as a less common side effect.

Interaction :

Anisindione, Warfarin, Dicumarol.

Hepatic Dose :

No dosage adjustments are recommended.
12/20/2023 07:21:50 Methyl Salicylate
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