Drug Index

Cefpodoxime

 
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Mechanism :

Cefpodoxime proxetil is an orally administered extended spectrum, semi-synthetic antibiotic of the cephalosporin class. Cephalosporins are bactericidal because of their inhibition of cell-wall synthesis.


Indication :

• Otitis media

• Community acquired pneumonia

• Tonsillitis

• Pharyngitis

• Enteric fever


Contraindications :

Cefpodoxime is contraindicated in patients with a known allergy to cefpodoxime or to the cephalosporin group of antibiotics.


Dosing :

<2 months: Safety and efficacy not established.

2 months-12 years: 5 mg/kg (Oral) every 12 hours for 5-10 days;

maximum dose: 200 mg/dose.

>12 years: 200 mg (Oral) every 12 hours for 5-10 days.


Adverse Effect :

Colitis, diarrhea, nausea, vomiting, headache and allergic reactions.


Interaction :

Absorption is decreased by antacids and H2 antagonists.


08/08/2019 17:09:18 Cefpodoxime
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